The aim of research work to formulate ORS with ginger for treatment of diarrhea. Diarrhea causes dehydration of body fluids. Dehydration happens when your body loses more fluid than you consume. This can happen due to many reasons, including excessive diarrhea or vomiting. When left untreated, dehydration can be dangerous. Oral rehydration salts is a treatment for dehydration. It involves drinking a beverage made of water, sugar, and electrolytes, specifically potassium and sodium. The beverage is called an oral rehydration solution (ORS).The goal of oral rehydration therapy is to replenish the body’s fluid levels. With the formula of ORS, the addition of Ginger plays a vital role to reduce the diarrheal effects. This research work involves the pre-formulation study followed by formulation, evaluation of product and different microbiological tests of ORS and Ginger. The culture media was prepared and microbe E.Coli added to it with ginger extract. The antimicrobial activity of sample was checked. The measurement of the optical density in the test tubes can be related to the bacterial growth, to detect the growth of the bacteria, we measured the optical density of the culture and later minimum inhibitory concentration is measured. The results showed our hypothesis that ginger inhibits the growth of Escherichia coli are therefore detected. Hence, it is confirmed that addition of ginger extract in ORS is effective treatment against diarrhea.
ORS, Electrolyte, Ginger, E.Coli, Antimicrobial Activity
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