Home > Pharmacy > Pharmaceutics > Volume-6 > Issue-5 > Formulation, Development, Characterization and in Vitro Study of Rosuvastatin Calcium Microemulsion

Formulation, Development, Characterization and in Vitro Study of Rosuvastatin Calcium Microemulsion

Call for Papers

Volume-7 | Issue-1

Last date : 24-Feb-2023

Best International Journal
Open Access | Peer Reviewed | Best International Journal | Indexing & IF | 24*7 Support | Dedicated Qualified Team | Rapid Publication Process | International Editor, Reviewer Board | Attractive User Interface with Easy Navigation

Journal Type : Open Access

First Update : Within 7 Days after submittion

Submit Paper Online

For Author

Research Area


Formulation, Development, Characterization and in Vitro Study of Rosuvastatin Calcium Microemulsion


Shubham Suresh Gaike | Prashant H Khade | Ashok Bhosale



Shubham Suresh Gaike | Prashant H Khade | Ashok Bhosale "Formulation, Development, Characterization and in Vitro Study of Rosuvastatin Calcium Microemulsion" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-5, August 2022, pp.177-191, URL: https://www.ijtsrd.com/papers/ijtsrd50424.pdf

The purpose of conducting this study was to prepare a microemulsion formulation of Rosuvastatin calcium (RC) for transdermal drug delivery. Oil in water microemulsion was formulated using Isopropyl myristate, Tween 20, and Propylene Glycol as oil, surfactant, and co-surfactant, respectively. The ideal proportion of surfactant: co-surfactant (Smix) was chosen by constructing pseudoternary diagrams. The microemulsion formulations, which proved to be stable after thermodynamic stability testing, were further evaluated for physical characteristics. Selected formulations were evaluated for droplet size, zeta potential, viscosity, and % drug content. Results suggested that optimized microemulsion formulation was thermodynamically stable and clear, droplet size and zeta potential was determined. In-vitro dissolution study for optimized microemulsion was performed and cumulative % drug release was determined.

Microemulsion, Transdermal drug delivery, Rosuvastatin calcium


IJTSRD50424
Volume-6 | Issue-5, August 2022
177-191
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

International Journal of Trend in Scientific Research and Development - IJTSRD having online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International Journal which provides rapid publication of your research articles and aims to promote the theory and practice along with knowledge sharing between researchers, developers, engineers, students, and practitioners working in and around the world in many areas like Sciences, Technology, Innovation, Engineering, Agriculture, Management and many more and it is recommended by all Universities, review articles and short communications in all subjects. IJTSRD running an International Journal who are proving quality publication of peer reviewed and refereed international journals from diverse fields that emphasizes new research, development and their applications. IJTSRD provides an online access to exchange your research work, technical notes & surveying results among professionals throughout the world in e-journals. IJTSRD is a fastest growing and dynamic professional organization. The aim of this organization is to provide access not only to world class research resources, but through its professionals aim to bring in a significant transformation in the real of open access journals and online publishing.

Thomson Reuters
Google Scholer
Academia.edu

ResearchBib
Scribd.com
archive

PdfSR
issuu
Slideshare

WorldJournalAlerts
Twitter
Linkedin