A film-forming gel is an innovative approach that is optional for conventional dosage forms applied to the skin. There are several transdermal formulations such as creams, ointment, gels, or patches, etc. But from these transdermal gel is more preferable than other transdermal formulations. The drug release is achieved by polymer solution which is directly applied on the skin in the form of liquid that forms a transparent invisible film in situ after solvent evaporation. Transdermal drug delivery system (TDDS) and dermal drug delivery system have been provided some desired performances that involve restriction of first metabolic pathways, enhancing drug bioavailability, decreasing dose frequency and stabilizing drug delivery profiles over conventional pharmaceutical dosage formulations. This review aimed to search for an optional dosage form to minimize skin irritation, enhance skin adhesion along with drug release, and improve patient compliances. Because of their irregular rheological behavior, polymeric gels are advantageous in case of ease of preparation, application, adhesion to the application surface, and capability to transport several varieties of drugs.
Film-forming gels, transdermal drug delivery, semi-solids
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