Home > Pharmacy > Other > Volume-7 > Issue-3 > UV Spectrophotometeric Analytical Method Development and Validation for the Determination of Telmisartan in Pharmaceutical Drug and Drug Formulation (Tablet Dosage Form)

UV Spectrophotometeric Analytical Method Development and Validation for the Determination of Telmisartan in Pharmaceutical Drug and Drug Formulation (Tablet Dosage Form)

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Volume-7 | Issue-3

Last date : 26-Jun-2023

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UV Spectrophotometeric Analytical Method Development and Validation for the Determination of Telmisartan in Pharmaceutical Drug and Drug Formulation (Tablet Dosage Form)


C. Shambiga | M. Menaka



C. Shambiga | M. Menaka "UV Spectrophotometeric Analytical Method Development and Validation for the Determination of Telmisartan in Pharmaceutical Drug and Drug Formulation (Tablet Dosage Form)" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-3, June 2023, pp.12-17, URL: https://www.ijtsrd.com/papers/ijtsrd56293.pdf

An easy, simple, specific, speedy, precise and accurate have been developed and validated for content determination of Telmisartan. This article based on validation of analytical method procedures which is established in ICH Q2 (R1).Telmisartan demonstrated the absorption maxima in at 291.2 nm and found was linear for a range of 5 µg/ml –25 µg/ml with correlation coefficient (LOD) of Telmisartan was found to be 2.09µg/ml and the limit of quantification (LOQ) of Telmisartan was found to be 6.34 µg/ml. The analytical method validation of the above proposed method was performed by carrying out precision and accuracy studies. The Accuracy percentage recovery on three different levels i.e. 25%, 50% and 75% was found to be 95.20%, 94.21% and 90.95% respectively. The proposed analytical method demonstrated good Intra precision (Repeatability) with relative standard deviations 2.54. The proposed analytical method was validated for the test parameter Specificity, Precision, Linearity and range, Ruggedness, Accuracy and recovery. The proposed method for content determination of Telmisartan in pure& tablet dosage form by UV spectrophotometer in pharmaceutical found easy, simple, accurate, precise and reproducible, economical and can be applied for the everyday quality control analysis.

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IJTSRD56293
Volume-7 | Issue-3, June 2023
12-17
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

International Journal of Trend in Scientific Research and Development - IJTSRD having online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International Journal which provides rapid publication of your research articles and aims to promote the theory and practice along with knowledge sharing between researchers, developers, engineers, students, and practitioners working in and around the world in many areas like Sciences, Technology, Innovation, Engineering, Agriculture, Management and many more and it is recommended by all Universities, review articles and short communications in all subjects. IJTSRD running an International Journal who are proving quality publication of peer reviewed and refereed international journals from diverse fields that emphasizes new research, development and their applications. IJTSRD provides an online access to exchange your research work, technical notes & surveying results among professionals throughout the world in e-journals. IJTSRD is a fastest growing and dynamic professional organization. The aim of this organization is to provide access not only to world class research resources, but through its professionals aim to bring in a significant transformation in the real of open access journals and online publishing.

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