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Gastroretentive Drug Delivery System: A Review

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Volume-7 | International Conference of Multidisciplinary Research

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Gastroretentive Drug Delivery System: A Review

Chetan Varade | Smita Aher | Rushikesh Bachhav

Chetan Varade | Smita Aher | Rushikesh Bachhav "Gastroretentive Drug Delivery System: A Review" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-7, December 2022, pp.578-587, URL: https://www.ijtsrd.com/papers/ijtsrd52341.pdf

The purpose of writing this review on gastroretentive drug delivery systems was to compile the recent literature with special focus on various gastroretentive approaches that have recently become leading methodologies in the field of site-specific orally administered controlled release drug delivery. In order to understand various physiological difficulties to achieve gastric retention, we have summarized important factors controlling gastric retention. Afterwards, we have reviewed various gastroretentive approaches designed and developed until now, i.e. high density (sinking), floating, bio- or mucoadhesive, expandable, unfoldable, super porous hydrogel and magnetic systems. Finally, advantages of gastroretentive drug delivery systems were covered in detail.

Gastric retention, Oral controlled release, Floating dosage form, Drug delivery system

Volume-6 | Issue-7, December 2022
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

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