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Natural Compounds as Adjuncts for Treating Colon Cancer through Apoptotic Pathway

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Natural Compounds as Adjuncts for Treating Colon Cancer through Apoptotic Pathway


Sarita Negi | Nikita Kaushik | Runjhun Mathur | Abhimanyu Kumar Jha



Sarita Negi | Nikita Kaushik | Runjhun Mathur | Abhimanyu Kumar Jha "Natural Compounds as Adjuncts for Treating Colon Cancer through Apoptotic Pathway" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-4, June 2021, pp.644-652, URL: https://www.ijtsrd.com/papers/ijtsrd42387.pdf

Cancer is one of the deadliest diseases which is caused when abnormal cells divide uncontrollably and destroy body tissue. Colorectal cancer (CRC), also known as colon cancer, is one of the most common type of cancers in humans is closely linked to the global cancer – related mortalities worldwide. The ongoing clinical treatment for colorectal cancer or colon cancer largely engages surgery and chemotherapy. But as there are many side effects and due to emergence of drug resistance, it has become very necessary to find novel and more effectual drugs for colon cancer treatment. Chemo prevention, a novel method for controlling cancer encompasses the use of specific natural products or synthetic chemical agents to reverse, suppress or prevent premalignancy before the development of invasive cancer. Many studies have signified that various natural products have efficacious anti CRC effects and may be used as substitutional chemotherapy agents for CRC therapy. Various natural compounds have been shown to be promising on the basis of their anti cancerous effects and low toxicity. In this review we summarise the natural compounds having anti CRC effects from distinct sources. This review suggest that they provide a novel opportunity for treatment of colon cancer.

Colon cancer, Apoptosis, Natural compounds, Caspases, Anti-cancer


IJTSRD42387
Volume-5 | Issue-4, June 2021
644-652
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

International Journal of Trend in Scientific Research and Development - IJTSRD having online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International Journal which provides rapid publication of your research articles and aims to promote the theory and practice along with knowledge sharing between researchers, developers, engineers, students, and practitioners working in and around the world in many areas like Sciences, Technology, Innovation, Engineering, Agriculture, Management and many more and it is recommended by all Universities, review articles and short communications in all subjects. IJTSRD running an International Journal who are proving quality publication of peer reviewed and refereed international journals from diverse fields that emphasizes new research, development and their applications. IJTSRD provides an online access to exchange your research work, technical notes & surveying results among professionals throughout the world in e-journals. IJTSRD is a fastest growing and dynamic professional organization. The aim of this organization is to provide access not only to world class research resources, but through its professionals aim to bring in a significant transformation in the real of open access journals and online publishing.

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