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A Review on Epileptic Treatment by Levetiracetam

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A Review on Epileptic Treatment by Levetiracetam


Parth Nikam | Rishikesh Bachhav



Parth Nikam | Rishikesh Bachhav "A Review on Epileptic Treatment by Levetiracetam" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-1, December 2021, pp.1-6, URL: https://www.ijtsrd.com/papers/ijtsrd46374.pdf

Background: Levetiracetam is a novel antiepileptic drug. It is marketed worldwide since 2000. Aim: The paper reviewed the mechanism of action, pharmacokinetics, adverse drug reactions, contraindications and uses of levetiracetam in the treatment of various types of epileptic seizures. Methods: Literature searches were done to identify relevant studies. Results: Levetiracetam acts by binding to the synaptic vesicle protein SV2A, thereby modulation of one or more of its actions and ultimately affecting neural excitability. It has less protein binding and lacks hepatic metabolism. In contrast to traditional therapy, it has a wide safety margin and does not require serum drug monitoring. It does not interact with other anti-epileptics. Conclusion: The above-mentioned favourable pharmacological benefits of LEV make it an important first-line or adjunctive therapy for epileptic seizures.

Levetiracetam, epilepsy, synaptic vesicle protein, seizures, efficacy, safety


IJTSRD46374
Volume-6 | Issue-1, December 2021
1-6
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

International Journal of Trend in Scientific Research and Development - IJTSRD having online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International Journal which provides rapid publication of your research articles and aims to promote the theory and practice along with knowledge sharing between researchers, developers, engineers, students, and practitioners working in and around the world in many areas like Sciences, Technology, Innovation, Engineering, Agriculture, Management and many more and it is recommended by all Universities, review articles and short communications in all subjects. IJTSRD running an International Journal who are proving quality publication of peer reviewed and refereed international journals from diverse fields that emphasizes new research, development and their applications. IJTSRD provides an online access to exchange your research work, technical notes & surveying results among professionals throughout the world in e-journals. IJTSRD is a fastest growing and dynamic professional organization. The aim of this organization is to provide access not only to world class research resources, but through its professionals aim to bring in a significant transformation in the real of open access journals and online publishing.

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