Simultaneous Estimation of Rifampicin and Isoniazide by Using UV Spectroscopy

Rameshwar Sanjay Bahirat; Harshal Laxman Bhagat; Dr. S. N. Kapse

Title:
Simultaneous Estimation of Rifampicin and Isoniazide by Using UV Spectroscopy

Authors:
Dr. S. N. Kapse | Rameshwar Sanjay Bahirat | Harshal Laxman Bhagat

Cite This Article :

Dr. S. N. Kapse | Rameshwar Sanjay Bahirat | Harshal Laxman Bhagat "Simultaneous Estimation of Rifampicin and Isoniazide by Using UV Spectroscopy" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-5, October 2024, pp.861-873, URL: https://www.ijtsrd.com/papers/ijtsrd69462.pdf

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Abstract :
A simple, accurate, and cost-effective UV spectroscopic method has been developed for the simultaneous estimation of rifampin in pharmaceutical formulations. Rifampin, a key anti-tuberculosis drug, exhibits characteristic absorption in the UV region, making it suitable for analysis via UV spectroscopy. The method involves determining the absorbance maxima of rifampin in a suitable solvent at specific wavelengths. The linearity of the drug was established in a given concentration range, and the method was validated according to ICH guidelines for parameters such as accuracy, precision, and reproducibility. This UV spectroscopic technique offers an efficient alternative to more complex analytical methods, providing reliable results for quality control and routine analysis in pharmaceutical environments.

Keywords :
rifampin, isoniazid, uv- spectroscopy, simultaneous estimation method, method development

Publication Details:

Unique Identification Number : IJTSRD69462

Published In : Volume-8 | Issue-5, October 2024

Page Number(s) : 861-873

Publisher Name : IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470

Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

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