Aims and ObjectivesTo study rheumatological manifestations in patients infected with HIV with regards to prevalence, pattern of involvement, correlation of various types of rheumatological syndromes with the grades of HIV infection and pattern of laboratory investigationsMethod: This study was conducted over a period of 6 months at Sassoon general hospital, Pune. A total of 100 HIV patients presenting with rheumatological complaints were enrolled in this study and analysed regarding clinical, laboratory and radiological features and disease activity score 28 was calculated. Results:There were 68 males and 32 females and Male to female ratio was 2.1:1. 78 % cases were in age group of 20 to 50 yrs that was sexually active group. A total of 75 % patients were in HIV stage 3 and 4 indicating high incidence of rheumatic manifestations with progression of HIV disease. The mean CD4 count was 264 mm3 and 62 % patient had CD4 between 200 to 499 mm3.The commonest rheumatic manifestation found was arthralgia (45%), while other common manifestations found in decreasing frequency were Arthritis (17%), myopathy (10%), spondyloarthropathy (9%), vasculitis (8%), painful articular syndrome (2%), Reiter’s arthritis (3%), psoriatic arthritis (2%), septic arthritis (2%) and rheumatoid arthritis (2%) cases. A raised ESR was seen in 81 % patients and raised CRP in 78% patients. Commonest radiological abnormality seen was soft tissue swelling and erosive changes of articular surface (11.1%). Arthritis due to varying aetiology in HIV patient usually has moderate disease activity as per DAS 28 ESR score hence it is less noticed by physicians.Conclusion: Physician should look for rheumatological manifestations in HIV, distinguish them from classic rheumatic diseases and do timely intervention to prevent disability and deformity and to improve the quality of life.
HIV, Rheumatological condition, clinical study
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