Background: Madhumeha, a subtype of Prameha, is extensively described in Ayurvedic texts and is considered equivalent to Diabetes Mellitus. One of its most debilitating complications is Diabetic Peripheral Neuropathy (DPN), a chronic microvascular disorder leading to sensory, motor, and autonomic dysfunction. Although classical Ayurvedic texts do not directly describe DPN, scattered references to Upadrava Vyadhis (~complications) of Prameha mirror neuropathic symptoms such as burning sensations, numbness, tingling, muscle wasting and weakness. Objective: This article critically reviews Ayurvedic concepts of Madhumeha in relation to DPN and thoroughly evaluates Ayurvedic management strategies in the light of contemporary biomedical evidence. Methods: Primary Ayurvedic classics alongside contemporary biomedical literature on DPN pathophysiology and its management were analysed through authentic Ayurveda and modern text as well as internet sources. Electronic databases (PubMed, Scopus, AYUSH Research Portal) were searched for clinical studies on Ayurvedic interventions for diabetic neuropathy, including randomized controlled trials (RCTs) and systematic reviews. Results: Ayurvedic descriptions of Avaranajanya (obstruction of Vata by Kapha/Pitta) and Dhatukshayaja (~tissue depletion) Madhumeha provide a coherent pathophysiological model for DPN, correlating with obstruction to nerve conduction and degenerative myelin sheath damage. Panchakarma, Rasayana herbs (Ashwagandha, Bala, Atibala, Guduchi), and parasurgical interventions (Jalaukavacharana) were found to alleviate neuropathic pain, improve nerve conduction velocity and enhance quality of life in diabetic patients. Conclusion: Ayurveda provides both preventive and therapeutic models for DPN as an Upadrava of Madhumeha. An integrative approach combining Nidana Parivarjana, Panchakarma, Rasayana formulations and Jalaukavacharana has promising potential in management of DPN. However, robust multi-centric RCTs are essential to validate efficacy and integrate these approaches into diabetes patients globally.
Ayurveda, Diabetic Peripheral Neuropathy, Jalaukavacharana, Madhumeha, Panchakarma, Prameha, Rasayana.
International Journal of Trend in Scientific Research and Development - IJTSRD having
online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International
Journal which provides rapid publication of your research articles and aims to promote
the theory and practice along with knowledge sharing between researchers, developers,
engineers, students, and practitioners working in and around the world in many areas
like Sciences, Technology, Innovation, Engineering, Agriculture, Management and
many more and it is recommended by all Universities, review articles and short communications
in all subjects. IJTSRD running an International Journal who are proving quality
publication of peer reviewed and refereed international journals from diverse fields
that emphasizes new research, development and their applications. IJTSRD provides
an online access to exchange your research work, technical notes & surveying results
among professionals throughout the world in e-journals. IJTSRD is a fastest growing
and dynamic professional organization. The aim of this organization is to provide
access not only to world class research resources, but through its professionals
aim to bring in a significant transformation in the real of open access journals
and online publishing.