In the current scenario due to evolving drug resistance of microbes/pathogens, especially the conditions like antibiotic resistance, residual toxicity, increased oxidative stress in cells and the concerns regarding harmful effects of allopathic medicines, nowadays novel and safer therapies viz., Ayurvedic, bacteriophage and others including Panchagavya therapy and nutritional immuno-modulatory approaches are gaining popularity and need special attention for their propagation as well as publicity. The traditional Ayurvedic system provides group of herbal drugs, amongst them medicated ghee is the foremost form of medicine prescribed in routine clinical practice, as ghee contains antioxidant and anti-toxic etc, properties in it. This dosage form is having its own importance as the selective extraction of active principles in lipid base is carried out. These lipophilic medicines might cross the blood-brain barrier. Panchagavya Ghrita is an Ayurvedic medicine consisting of five components, namely, Goksheera, Goghrita, Godadhi, Gomutra, Gomaya rasa. Clinically, it has been recommended for the treatment of Apasmara, Jvara, Pandu and Kamala. These products comprise antioxidant, antibacterial, anti-carcinogenic, hepatoprotective, wound-healing and immune-stimulant properties. It has the potential to reduce the production of free radicals. In the present paper, an attempt is made to review the Panchagavya ghrita from various classics and its clinical utility in all age groups with different dosage forms based on conditions.
Panchagavya ghrita, Goksheera, Goghrita, Gomutra, Godadhi Gomaya rasa, antioxidant, hepatoprotective
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