The study investigated the effect of contextual teaching-learning approach (CTLA) on chemistry students’ academic retention in secondary schools in Anambra State, Nigeria. A pre-test, posttest quasi-experimental design was used involving a sample of 130 students drawn from six education zones in the state. The instrument known as contextual learning chemistry retention test (CLCRT), validated by two experts with a reliability coefficient of 0.84 was used for data collection. Two research questions and two hypotheses guided the study. Mean and standard deviation were used to answer the research questions, while t-test was used to test the null hypotheses at P<0.05. The result revealed that CTLA had significant effect on students’ academic retention in chemistry. Finding implies there is need for chemistry teachers should adopt the use of contextual teaching-learning approach to improve the performance of students in chemistry.
                                
                                
                                    
                                    Science Technology, Contextual Teaching-Learning Approach, Gender, Chemistry Instruction
                                
                                
                                
                                
                                    
                                        
                                        
                                        
                                        
                                            
                                                
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