Optimization plays a key role in environmental engineering parameters since the best system performance mainly is on optimum point or optimum range. The majority of wastewater treatment processes are multi-variable and optimization through the classical method is inflexible, unreliable and time-consuming. Thus, response surface methodology (RSM), as a very efficient design and widely used technique, can be adapted for optimization of various parameters in wastewater treatment processes. RSM is a practical mathematical and statistical tool that can be employed for analyzing the effects of several independent factors on the treatment process in order to obtain the maximum benefit from the process. Recently, several water and wastewater treatment processes have been optimized for treatment different type of wastewaters via RSM including; textile dye wastewater, tannery wastewater, industrial paint wastewater, landfill leachate, olive oil wastewater, and palm oil mill effluent. The present study focuses on the usability and effectiveness of RSM for process parameters modeling and optimization in wastewater treatment studies. In this paper, some of the RSM studies were reviewed in order to verify the usability of RSM and its limitations.
                                
                                
                                    
                                    Design of experiments, Optimization, Pulp and Paper Industry, Response Surface Methodology, Wastewater.
                                
                                
                                
                                
                                    
                                        
                                        
                                        
                                        
                                            
                                                
                                                    International Journal of Trend in Scientific Research and Development - IJTSRD having
                                                    online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International
                                                    Journal which provides rapid publication of your research articles and aims to promote
                                                    the theory and practice along with knowledge sharing between researchers, developers,
                                                    engineers, students, and practitioners working in and around the world in many areas
                                                    like Sciences, Technology, Innovation, Engineering, Agriculture, Management and
                                                    many more and it is recommended by all Universities, review articles and short communications
                                                    in all subjects. IJTSRD running an International Journal who are proving quality
                                                    publication of peer reviewed and refereed international journals from diverse fields
                                                    that emphasizes new research, development and their applications. IJTSRD provides
                                                    an online access to exchange your research work, technical notes & surveying results
                                                    among professionals throughout the world in e-journals. IJTSRD is a fastest growing
                                                    and dynamic professional organization. The aim of this organization is to provide
                                                    access not only to world class research resources, but through its professionals
                                                    aim to bring in a significant transformation in the real of open access journals
                                                    and online publishing.