Optimization of Withania Somnifera and Ocimum Sanctum Combinations and Evaluate their Synergistic Effect

Manisha; Neera Raghav | Heena Dahiya | Nitika Mor; Khushboo

Title:
Optimization of Withania Somnifera and Ocimum Sanctum Combinations and Evaluate their Synergistic Effect

Authors:
Khushboo | Manisha | Neera Raghav | Heena Dahiya | Nitika Mor

Cite This Article :

Khushboo | Manisha | Neera Raghav | Heena Dahiya | Nitika Mor "Optimization of Withania Somnifera and Ocimum Sanctum Combinations and Evaluate their Synergistic Effect" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-9 | Issue-4, August 2025, pp.308-312, URL: https://www.ijtsrd.com/papers/ijtsrd97207.pdf

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Abstract :
Natural compounds' varied structures and diverse biological effects make them an essential source for medication development. Among these, Ocimum sanctum (tulsi) and Withania somnifera (ashwagandha) are well-known medicinal herbs with therapeutic uses in traditional medicine, especially because of their enzyme-modulating, anti-inflammatory, and antioxidant properties. In order to create a stable and potent polyherbal formulation, the present work focussed on the systematic standardization and optimization of W. somnifera (W.S.) and O. sanctum (O.S.). Both their synergistic and individual effects were assessed analytically. When Withania somnifera and Ocimum sanctum are combined, W.S.'s solubility and bioactivity are greatly increased. The results support the scientific validation of traditional medicines for certain conditions and highlight the significance of physicochemical profiling in optimizing herbal mixtures.

Keywords :
Ashwagandha, Tulsi, solubility, synergistic, therapeutic.

Publication Details:

Unique Identification Number : IJTSRD97207

Published In : Volume-9 | Issue-4, August 2025

Page Number(s) : 308-312

Publisher Name : IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470

Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

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