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Lymphocytopenia and COVID19: A Literature Review

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Lymphocytopenia and COVID19: A Literature Review


Shatabdi Dey | P. K Sahoo



Shatabdi Dey | P. K Sahoo "Lymphocytopenia and COVID19: A Literature Review" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-2, February 2021, pp.213-217, URL: https://www.ijtsrd.com/papers/ijtsrd38373.pdf

The novel coronavirus SAR-CoV-2 has resulted in huge wave of worldwide fear by its contagious nature, virulence and high mortality. Persistence condition of the disease with T-cells and Natural killer cells exhaustion leads to Lymphopenia or Lymphocytopenia. Lymphocytopenia is a condition of low lymphocyte count in the blood. Lymphocytopenia is an important adverse effect of COVID-19 as well as negative prognostic marker in many malignancies. It leads to hyper activation of immune system that can cause immunosuppression and promote cytokine storm that eventually leads to multi-organ failure and death. Restoration of lymphocytes and its function would be helpful to boost the immune response against COVID-19 disease. This review analyses the possible causes that may lead to the lymphocyte reduction in COVID-19 patients, and highlighting the possible therapeutic strategies that will help to control and prevent lymphocytopenia in COVID-19 patients.

COVID-19, SAR-CoV-2, T-lymphocytes, NK cells, Lymphocytopenia, cytokine storm


IJTSRD38373
Volume-5 | Issue-2, February 2021
213-217
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

International Journal of Trend in Scientific Research and Development - IJTSRD having online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International Journal which provides rapid publication of your research articles and aims to promote the theory and practice along with knowledge sharing between researchers, developers, engineers, students, and practitioners working in and around the world in many areas like Sciences, Technology, Innovation, Engineering, Agriculture, Management and many more and it is recommended by all Universities, review articles and short communications in all subjects. IJTSRD running an International Journal who are proving quality publication of peer reviewed and refereed international journals from diverse fields that emphasizes new research, development and their applications. IJTSRD provides an online access to exchange your research work, technical notes & surveying results among professionals throughout the world in e-journals. IJTSRD is a fastest growing and dynamic professional organization. The aim of this organization is to provide access not only to world class research resources, but through its professionals aim to bring in a significant transformation in the real of open access journals and online publishing.

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