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Exploring Molecular Targets for Repositioning of Hypertensive Drugs

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Exploring Molecular Targets for Repositioning of Hypertensive Drugs


Bhawna Singh | Asmita Das



Bhawna Singh | Asmita Das "Exploring Molecular Targets for Repositioning of Hypertensive Drugs" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-3, April 2021, pp.635-640, URL: https://www.ijtsrd.com/papers/ijtsrd39910.pdf

Drug repositioning or drug repurposing or drug profiling is the discovery of new applications for approved or failed drug.. Drug repositioning is the development of new approved drug applications. The cost of bringing a medicine to the market is around one million which include clinical and preclinical trials. Repositioning of drugs help in cutting down costs as well as time involve in intial validation and authorization. The procedure involved in Drug repositioning is generally performed during the drug development phase to modify or extend an active molecule's distribution line. On a fundamental level, repositioning opportunities exist because drugs perturb multiple biological entities and engage themselves in multiple biological processes. Therefore, a drug can play multiple roles or perform a various mode of actions that are responsible for its pharmacology. Hypertension, is a condition that causes increase in the risk of cardiovascular diseases. In this study an attempt has been made to reposition hypertensive drugs for different diseases by exploring molecular targets of hypertensive drugs. Consider that they often need to be administered for long periods of time, often over whole life time Side effects although present, have been found safe enough to be used for such long durations, hence repurposing these drugs for other diseases may be beneficial with limited side effects.

HCQ, hypertension, cancer


IJTSRD39910
Volume-5 | Issue-3, April 2021
635-640
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

International Journal of Trend in Scientific Research and Development - IJTSRD having online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International Journal which provides rapid publication of your research articles and aims to promote the theory and practice along with knowledge sharing between researchers, developers, engineers, students, and practitioners working in and around the world in many areas like Sciences, Technology, Innovation, Engineering, Agriculture, Management and many more and it is recommended by all Universities, review articles and short communications in all subjects. IJTSRD running an International Journal who are proving quality publication of peer reviewed and refereed international journals from diverse fields that emphasizes new research, development and their applications. IJTSRD provides an online access to exchange your research work, technical notes & surveying results among professionals throughout the world in e-journals. IJTSRD is a fastest growing and dynamic professional organization. The aim of this organization is to provide access not only to world class research resources, but through its professionals aim to bring in a significant transformation in the real of open access journals and online publishing.

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