Method Devlopment of Apremilast API in Methanol by UV Visible Spectroscopy
A simple, precise, accurate, cost effective stability indicating UV Spectrophotometric method has been developed for the estimation of Apremilast. Apremilast shows highest max at 340 nm. Beer s law linearity response was found over a concentration range of 10 60 µg mL with good correlation coefficient r2 = 0.9994 . The Proposed spectrophotometric method was validated as per the ICH Q1A R2 guidelines. Hence this method can be safely be employed for the routine quality control analysis of Apremilast.
Apremilast, Method Development, uv visible spectroscopy
Deepak Chandra Sharma | G. Rajan | Pranshu Tangri | Preeti Kothiyal