<b>Clinical Research A Big Data Science Approach</b> “Big data” is defined as the collection of large and complex datasets available in structured, semi structured, and unstructured form which are dif cult to process using traditional database management tools or data processing applications. Big Data is also defined from 5 Vs which refers to Volume, Variety, Velocity, Veracity and Value .Clinical Research is one of the most important as well as promising part of health research. This article provides an overview on some specific aspects of clinical research when adapted to Big Data Science pathways which could be utilized for transforming millions of data points into predictions and simulation to provide cost effective medicines in reduced timelines. This article also highlights the opportunities and challenges that Big Data brings with it. Big Data, Clinical Research, Data Science, Clinical Trials 1075-1078 Issue-2 Volume-2 Dr. Elton Mathias | Dr. Roveena Goveas | Manish Rajak