<b>Critical Analysis on Vatika Grahani W.S.R. to Irritable Bowel Syndrome</b> Background Pittadharakala situated between Pakvasaya and Amasaya is known as Grahani. Agni resides in the Grahani, Strength of Grahani is Agni hence when Agni is vitiated Grahani is also vitiated. The term Grahani as a disease entity specifically used for the ailment Grahanigada, which manifest due to malfunctioning of Grahani. Grahanidosha refers to diseases located in Grahani. Aims and objective To critically analyze Vatika Grahani and Irritable Bowel Syndrome. Materials and Methods Ayurvedic classics were scrutinized regarding the reference for Grahani. Other research journals, papers related to Grahani are also explored along with Irritable Bowel Syndrome as per modern correlation. Later, supportive correlation and reliable hypothesis are made regarding Vatika Grahani and Irritable Bowel Syndrome. Discussion and Conclusion Grahani is disease of Annavaha srotas related to Agni and lifestyle. Normally, it restrains the downward movement of undigested food and after the digestion it releases the food through its lumen. In the abnormal condition, when it gets vitiated because of weakness of Agni Power of digestion it releases the food in undigested form only. Grahani Dosha refers to diseases located in Grahani. Symptoms of Vataja Grahani and Irritable Bowel Syndrome have similarities, thus can be correlated. They are mainly treated by Agnivardhaka drugs with Deepana and Pachana properties along with Medhya drugs. Irritable Bowel Syndrome IBS is a functional disorder of the intestine characterized by alteration of the bowel habits and abdominal pain. There is no morphologic, histologic, microbiologic or biochemical abnormalities in IBS. Changes in gut motility are observed in several studies though they poorly correlate with the symptoms. Emotional stress is seen to aggravate the motility disorder thus, a one size fits all approach to treatment is inappropriate for most patients. Vatika Grahani, Agni, Irritable Bowel Syndrome 18-20 Issue-3 Volume-7 V M Arya | P T Parvana | Kamath Nagaraj