<b>Evaluation of Drug Utilization Pattern of Antimicrobial Agents in Hyderabad Adult Patients of Otorhinolaryngology ENT , in a Tertiary Care Teaching Hospital Telangana</b> The Ear, Nose and Throat ENT infections can be caused by a variety of microorganisms such as bacteria, fungi and viruses. Their treatment involves the use of appropriate antimicrobial agents and inappropriate use is closely linked to antibiotic resistance. Hence, present study was planned to evaluate the prescribing pattern of antimicrobials agents in Hyderabad adult patients of Otorhinolaryngology ENT , in a tertiary care teaching hospital Telangana. A cross sectional prospective observational study carried out over a period of six month from Jan 2018 to June 2018. Total 250 patients were selected during our study and were analyzed on the basis of inclusion and exclusion criteria. All the patients with antibiotics in their prescriptions, between 18 65 years of age were included in the study. Data were collected in Case Record Form CRF . In this study, total 250 Hyderabad adult patients’ prescriptions were analyzed. Among them 148 59.20 were male and 102 40.80 were female. The maximum number of patients were found to be 18 30 years of age group. Among all ENT infections, Most common infection was Chronic Suppurative Otitis Media CSOM . The most commonly prescribed antimicrobial agents were Ceftriaxone n=152, 60.80 followed by Amikacin n=96 38.40 Metronidazole n=65 26 and Ciproflocxacin n=35, 14 . Our study concluded that Beta lactams, Amikacin, Metronidazole were most commonly prescribed antibiotics and also included in essential drug list. The use of the generic names was found to be satisfactory, but the average number of drug per prescription was high. Prescribing Pattern, ENT Infection, Antimicrobial agents 771-775 Issue-4 Volume-6 Dr. S. Venkata Saibaba | Dr. B. Prabhakar Reddy | Dr. Y. Karnakar Reddy | Dr. B. Tirupathi