<b>Concept of Chemical Science in Vedic Literature</b> The whole Sanskrit Literature is enriched with different sources of knowledge from the beginning itself. Moreover the Vedic literature is something different from the classical literature which stands to prove the origin and development of science and technology of the then period. In this paper an effort has made to highlight the concept of Chemical science as reflected in Vedic literature Chemical Science, Satva, Rajas, Tamas, Pritirupa, Apritirupa, Vi adarupa, Padartha, Anu, Paramanu, Bhautika Parivartana, Rasayanika Parivartana, Rajata, Tamra, Lauha, Bhasma, Yajurveda, Atharvaveda, Ayurveda, Rasaka, Lohavedha, Dehavedha, Kayakalpa, Rasaratna Samucaya 43-45 Issue-4 Volume-5 Dr. Debajyoti Jena