Studies on Phytochemicals, Antioxidant and Anticancer Potentials of Evolvulus Alsinoides using Lung Cancer Cell Line
The main objective of this study was to evaluate the phytochemicals, antioxidant potentials and anticancer property of Evolvulus alsinoides. Initially, plant extract was prepared using different solvents includes petroleum ether, ethanol and ethyl acetate. The antioxidant potential of the selected plant extract was assessed by Super oxide radical assay, Hydroxyl radical assay and DPPH assays and the results were analyzed. The anticancer property was observed against lung cancer cell line, A 549. From the results it was found that, Alkaloids, Steroids, Flavonoids, Tannins Phenol, Proteins, Carbohydrate and Glycosides are present in the ethanolic extract of the plant. No significant compounds could be detected in other extracts including petroleum ether and ethyl acetate. DPPH assay and Ferric thiocyanate method clearly reveals that, this plant extract has significant antioxidant potential in dose dependent manner. It also showed notable inhibitory potential against the growth of the lung cancer cells.
phytochemicals, antioxidant, anticancer, lung cancer
Shaleesha A. Stanley | T. Yazhini