<b>A Comparative Evaluation of Antegonial Notch Depth, Symphysis Morphology, Ramus and Mandibular Morphology in Different Growth Patterns in Angle’s Class I Malocclusion</b> Introduction Growth and development has always remained the topic of interest for various researchers as it has a direct effect on the orthodontic diagnosis and treatment planning. A reliable method for growth prediction would be a key asset to the orthodontist. The depth of antegonial notch and mandibular morphology are important indicators of growth pattern. Materials and methods The sample included 80 lateral cephalograms with Angle’s class I malocclusion ANB=2–4°, aged 18 30 years. The adults were categorized as average growers GO GN to SN = 28–34° , horizontal growers GO GN to SN = 28° and vertical growers GO GN to SN = 34° . The antegonial notch depth, symphysis height, symphysis depth, ratio height of symphysis depth of symphysis , angulation of symphysis, inclination of symphysis, ramus height, ramus width, mandibular and body length were assessed. To evaluate statistical significance for each parameter amongst all the three groups, one way ANOVA test was applied. Results A comparative evaluation revealed statistically significant difference with antegonial notch depth, symphysis height, symphysis depth, ratio height of symphysis depth of symphysis , angulation of symphysis, inclination of symphysis, ramus height and ramus width. Conclusion Antegonial notch depth is greater in the vertical growers as compared to horizontal and average growers. Symphysis morphology in horizontal growth pattern is associated with short height, large depth, small ratio height depth , and larger angle. Conversely, symphysis with a larger height, smaller depth, larger ratio, and a smaller angle is found in vertical growers. Ramus height and width is greater in horizontal growers as compared to the vertical growers. antegonial notch, average growth pattern, horizontal growth pattern, vertical growth pattern, ramus morphology, symphysis morphology and mandibular morphology 1588-1595 Issue-4 Volume-4 Dr. Riyazhusein Kisan | Dr. Amit Nehete | Dr. Nitin Gulve | Dr. Kunal Shah | Dr. Shivpriya Aher