<b>Knowledge Regarding Sexually Transmitted Disease STD’s among B.Sc. Nursing First Year Students</b> Sexually transmitted infections STIs are the infections which are mainly transmitted through sexual intercourse. The common STIs which we come across in daily practice are gonorrhoea, cancroids, syphilis, and Chlamydia infections which can be cured and others such as HIV, genital herpes, HPV, and hepatitis B infection which cannot be cured but can be modified with the available treatments. Sexually transmitted diseases are a major health problem affecting mostly young people, not only in developing, but also in developed countries. It is the major health problem in developing and developed countries. They cause serious health economic and social consequences. The main aim of the study is to assess the knowledge regarding sexually transmitted disease among B.Sc. nursing first year students. A quantitative descriptive survey study was conducted to assess the knowledge regarding STD’s and to find the association between knowledge score with selected demographic variable. Total 100 study participants were selected by purposive sampling technique from B.Sc. nursing first year, Faculty of Nursing, SGT University, Gurugram, Haryana. Data revealed most of the study participants 96 had good knowledge regarding sexually transmitted disease and 4 study participants had average knowledge regarding sexually transmitted disease. It was concluded that B.Sc. nursing first year students had good knowledge regarding sexually transmitted disease. Knowledge, Sexually transmitted disease, B.Sc. nursing students 10-12 Issue-1 Volume-4 Sehrawat V | Bisht R