<b>Bacteriological Profile of Skin Moisturizing Lotions during use and its Potential Hazards</b> Skin moisturizing lotions serve as the essential needs of modern lifestyle. Moreover its composition serves as luxurious source for the growth of varied micro organisms as it contain special additives like plant extracts, fatty acids and vitamins. Hence the present investigation was carried out to evaluate and screen the bacterial contaminants from skin moisturizing lotions and to study its antibiotic resistance pattern. A total of 22 different types of skin moisturizing lotions representing different brands were collected. Out of which, 8 samples showed presence of two potential bacterial contaminants including 7 isolates of Staphylococcus aureus and 8 isolates Pseudomonas aeruginosa. The results of the test revealed that all the isolates of S. aureus were sensitive against tested antibiotics while 2 isolates of P. aeruginosa were resistant to Gentamycin and Carbenicillin and 1 to Levofloxacin. The findings of this study conclude that skin moisturizing lotions may contain bacterial contaminants such Staphylococcus aureus and Pseudomonas aeruginosa in tested products posing a serious threat for the consumers. When the bacterial contaminants were tested against Neem and Daru Haldi extracts, it was found that the extracts were effective against it. Skin moisturizing lotion, Bacterial contaminants, Staphylococcus aureus, Pseudomonas aeruginosa 271-276 Issue-6 Volume-1 Namrata G. Shukla | Pranita A. Gulhane | Ashok V. Gomashe