<b>Formulation and Evaluation of Antibacterial, Antifungal Cream of Garlic Oil</b> Plan The main aim of our research was to develop a novel cream formulation consisting of Garlic oil for the treatment of secondary skin infections. Prologue Topical route is most suitable route for skin infections. The development of topical drug delivery systems designed to have systemic effects appears to be beneficial for a number of drugs on account of the several advantages over conventional routes of drug administration. Methodology A novel cream formulation consisting of Garlic oil was prepared. The formulation was subjected to in vitro diffusion studies. Microbiological studies were performed to find out the safety of materials used in the formulation. Result The developed cream consisting of Garlic oil was found to be safe and effective for the treatment of skin infections. Antibacterial cream, Garlic oil, Antifungal cream 849-852 Issue-1 Volume-3 Amol Pimpale