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Method Devlopment of Apremilast (API) in Methanol by UV-Visible Spectroscopy

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Volume-3 | Issue-2

Last date : 25-Feb-2019

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Method Devlopment of Apremilast (API) in Methanol by UV-Visible Spectroscopy

Deepak Chandra Sharma | G. Rajan | Pranshu Tangri | Preeti Kothiyal

Deepak Chandra Sharma | G. Rajan | Pranshu Tangri | Preeti Kothiyal "Method Devlopment of Apremilast (API) in Methanol by UV-Visible Spectroscopy" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-3 , April 2018, URL: http://www.ijtsrd.com/papers/ijtsrd9675.pdf

A simple, precise, accurate, cost effective stability indicating UV Spectrophotometric method has been developed for the estimation of Apremilast. Apremilast shows highest ?max at 340 nm. Beer's law (linearity response) was found over a concentration range of 10-60 µg /mL with good correlation coefficient (r2 = 0.9994). The Proposed spectrophotometric method was validated as per the ICH Q1A (R2) guidelines. Hence this method can be safely be employed for the routine quality control analysis of Apremilast.

Apremilast, Method Development, uv-visible spectroscopy


Volume-2 | Issue-3 , April 2018

2456-6470

IJTSRD9675