The present study was carried out to isolate the bacterial species from the urine sample collected from 30 female patients with urinary tract infections and to test the antibiotic sensitivity pattern of the isolated bacteria. Samples were collected from the Government Hospital, Pattukkottai, Thanjavur District, Tamilnadu, India. The collected urine samples were streak plated different agar media. The bacterial colonies on the plates were subject to motility, gram staining and biochemical tests. E. coil, Klebsiella and Staphylococcus aureus were identified and confirmed using Bergey’s manual of systematic bacteriology. Totally 29 isolates were obtained in which 18 were E. coli, 8 Klepsiella Sp and 3 Staphyococcus aureus species. Then the bacterial species were tested against the antibiotics such as Cefuroxime, Gentamicin, Nitrofurantion, Amaxicillium and Tetracycline. The antibiotic, gentamicin showed maximum activity against all the bacterial species followed by Cefuroxime, Nitrofurantioin, Amoxyullum and Tetracycline. Thus the present study reveals the importance of selecting a particular antibiotic for the treatment of urinary tract infections of female patients, those who are highly prone to the infection caused by the urinary tract infecting bacterial species. As drug resistance among bacterial pathogens is an evolving process, regular surveillance and monitoring is necessary to provide physician’s knowledge on the updated and most effective empirical treatment of UTIs. Periodic reassessment of in vitro susceptibility pattern of ordinary pathogens to serve as a guide for antibiotic therapy since these organisms exhibit resistance to first - line drugs used for UTI infection.
E.coli, Klepsiella Sp,Staphyococcus aureus Cefuroxime, Nitrofurantioin, Amoxyullum and Tetracycline, Urine
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